Research Summary

Oligonucleotide therapeutics are a class of therapeutic agents that utilize short DNA or RNA molecules, typically consisting of 20-50 nucleotides, to modulate gene expression or target specific disease-causing molecules in the body. These therapeutics can be designed to selectively bind to messenger RNA (mRNA), microRNA (miRNA), or other nucleic acid targets, interfering with their function or promoting specific biological processes. Oligonucleotide therapeutics can act by various mechanisms, including downregulating gene expression through mRNA degradation or blocking translation, correcting abnormal splicing of mRNA, or selectively inhibiting specific proteins or enzymes involved in disease processes. This versatile class of therapeutics has shown promise in treating a wide range of diseases, including genetic disorders, viral infections, neurological disorders, and cancer. Oligonucleotide therapeutics are typically delivered to target tissues or cells through various delivery systems, such as lipid nanoparticles or conjugates. Their development is an active area of research and clinical investigation, with several oligonucleotide-based drugs already approved for clinical use and many more in development.

According to DIResearch's in-depth investigation and research, the global Oligonucleotide Therapeutics market size was valued at XX Million USD in 2024 and is projected to reach XX Million USD by 2032, with a CAGR of XX% (2025-2032). Notably, the China market has changed rapidly in the past few years. By 2024, China's market size is expected to be XX Million USD, representing approximately XX% of the global market share. By 2032, it is anticipated to grow further to XX Million USD, contributing XX% to the worldwide market share.

The major global  manufacturers of Oligonucleotide Therapeutics include Biogen, Sarepta Therapeutics, Bausch & Lomb, Jazz Pharmaceuticals, Alnylam Pharmaceuticals, Akcea Therapeutics, Dynavax Technologies, Kastle therapeutics etc. The global players competition landscape in this report is divided into three tiers. The first tier comprises global leading enterprises that command a substantial market share, hold a dominant industry position, possess strong competitiveness and influence, and generate significant revenue. The second tier includes companies with a notable market presence and reputation; these firms actively follow industry leaders in product, service, or technological innovation and maintain a moderate revenue scale. The third tier consists of smaller companies with limited market share and lower brand recognition, primarily focused on local markets and generating comparatively lower revenue.

This report studies the market size, price trends and future development prospects of Oligonucleotide Therapeutics. Focus on analysing the market share, product portfolio, prices, sales, revenue and gross profit margin of global major manufacturers, as well as the market status and trends of different product types and applications in the global Oligonucleotide Therapeutics market. The report data covers historical data from 2020 to 2024, based year in 2025 and forecast data from 2026 to 2032.

The regions and countries in the report include US, Germany, Japan, China, France, UK, South Korea, Canada, Italy, Russia, Mexico, Brazil, India, Vietnam, Thailand, South Africa and other regions, covering the Oligonucleotide Therapeutics market conditions and future development trends of key regions and countries, combined with industry-related policies and the latest technological developments, analyze the development characteristics of Oligonucleotide Therapeutics industries in various regions and countries, help companies understand the development characteristics of each region, help companies formulate business strategies, and achieve the ultimate goal of the company's global development strategy.

The data sources of this report mainly include the National Bureau of Statistics, customs databases, industry associations, corporate financial reports, third-party databases, etc. Among them, macroeconomic data mainly comes from the National Bureau of Statistics, International Economic Research Organization; industry statistical data mainly come from industry associations; company data mainly comes from interviews, public information collection, third-party reliable databases, and price data mainly comes from various markets monitoring database.

Global Key Manufacturers of Oligonucleotide Therapeutics Include:

Biogen

Sarepta Therapeutics

Bausch & Lomb

Jazz Pharmaceuticals

Alnylam Pharmaceuticals

Akcea Therapeutics

Dynavax Technologies

Kastle therapeutics

Oligonucleotide Therapeutics Product Segment Include:

Antisense Oligonucleotide

Aptamer

Others

Oligonucleotide Therapeutics Product Application Include:

Neuromuscular Diseases

ATTR

Hepatic VOD

Others

Chapter Scope

Chapter 1: Product Research Range, Product Types and Applications, Market Overview, Market Situation and Trend

Chapter 2: Global Oligonucleotide Therapeutics Industry PESTEL Analysis

Chapter 3: Global Oligonucleotide Therapeutics Industry Porter's Five Forces Analysis

Chapter 4: Global Oligonucleotide Therapeutics Major Regional Market Size (Revenue) and Forecast Analysis

Chapter 5: Global Oligonucleotide Therapeutics Competitive Analysis of Key Manufacturers (Revenue, Market Share, Regional Distribution and Industry Concentration)

Chapter 6: Global Oligonucleotide Therapeutics Revenue and Forecast Analysis by Product Type

Chapter 7: Key Company Profiles (Product Portfolio, Revenue and Gross Margin)

Chapter 8: Industrial Chain Analysis, Oligonucleotide Therapeutics Different Application Market Analysis (Revenue and Forecast) and Sales Channel Analysis

Chapter 9: Research Findings and Conclusion

Chapter 10: Methodology and Data Sources

Table 1： Oligonucleotide Therapeutics Industry Development Status

Table 2： Oligonucleotide Therapeutics Industry Development Trends

Table 3： Global Oligonucleotide Therapeutics Revenue and Growth Rate (CAGR) by Country: 2024 VS 2025 VS 2032 (US$ Million)

Table 4： Global Oligonucleotide Therapeutics Revenue by Country (2020-2025) & (US$ Million)

Table 5： Global Oligonucleotide Therapeutics Revenue Market Share by Country (2020-2025)

Table 6： Global Oligonucleotide Therapeutics Revenue Forecast by Country (2026-2032) & (US$ Million)

Table 7： Global Oligonucleotide Therapeutics Revenue Market Share Forecast by Country (2026-2032)

Table 8： Global Oligonucleotide Therapeutics Market Revenue by Key Manufacturers (2021-2025) & (US$ Million)

Table 9： Global Oligonucleotide Therapeutics Revenue Market Share by Key Manufacturers (2021-2025)

Table 10： Global Key Manufacturers Headquarter and Key Area Sales

Table 11： Market Mergers & Acquisitions, Expansion

Table 12： Global Oligonucleotide Therapeutics Market Size and Growth Rate (CAGR) Analysis by Type: 2024 VS 2025 VS 2032 (US$ Million)

Table 13： Global Oligonucleotide Therapeutics Revenue Analysis by Type (2020-2025) & (US$ Million)

Table 14： Global Oligonucleotide Therapeutics Revenue Forecast Analysis by Type (2026-2032) & (US$ Million)

Table 15： Biogen Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

Table 16： Biogen Oligonucleotide Therapeutics Product Portfolio

Table 17： Biogen Oligonucleotide Therapeutics Revenue (US$ Million), Gross Margin and Market Share (2021-2025)

Table 18： Sarepta Therapeutics Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

Table 19： Sarepta Therapeutics Oligonucleotide Therapeutics Product Portfolio

Table 20： Sarepta Therapeutics Oligonucleotide Therapeutics Revenue (US$ Million), Gross Margin and Market Share (2021-2025)

Table 21： Bausch & Lomb Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

Table 22： Bausch & Lomb Oligonucleotide Therapeutics Product Portfolio

Table 23： Bausch & Lomb Oligonucleotide Therapeutics Revenue (US$ Million), Gross Margin and Market Share (2021-2025)

Table 24： Jazz Pharmaceuticals Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

Table 25： Jazz Pharmaceuticals Oligonucleotide Therapeutics Product Portfolio

Table 26： Jazz Pharmaceuticals Oligonucleotide Therapeutics Revenue (US$ Million), Gross Margin and Market Share (2021-2025)

Table 27： Alnylam Pharmaceuticals Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

Table 28： Alnylam Pharmaceuticals Oligonucleotide Therapeutics Product Portfolio

Table 29： Alnylam Pharmaceuticals Oligonucleotide Therapeutics Revenue (US$ Million), Gross Margin and Market Share (2021-2025)

Table 30： Akcea Therapeutics Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

Table 31： Akcea Therapeutics Oligonucleotide Therapeutics Product Portfolio

Table 32： Akcea Therapeutics Oligonucleotide Therapeutics Revenue (US$ Million), Gross Margin and Market Share (2021-2025)

Table 33： Dynavax Technologies Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

Table 34： Dynavax Technologies Oligonucleotide Therapeutics Product Portfolio

Table 35： Dynavax Technologies Oligonucleotide Therapeutics Revenue (US$ Million), Gross Margin and Market Share (2021-2025)

Table 36： Kastle therapeutics Basic Company Profile (Employees, Areas Service, Competitors and Contact Information)

Table 37： Kastle therapeutics Oligonucleotide Therapeutics Product Portfolio

Table 38： Kastle therapeutics Oligonucleotide Therapeutics Revenue (US$ Million), Gross Margin and Market Share (2021-2025)

Table 39： Upstream Key Raw Material Price List

Table 40： Oligonucleotide Therapeutics Raw Material Suppliers and Contact Information

Table 41： Global Oligonucleotide Therapeutics Market Size and Growth Rate (CAGR) by Application: 2024 VS 2025 VS 2032 & (US$ Million)

Table 42： Global Oligonucleotide Therapeutics Revenue Analysis by Application (2020-2025) & (US$ Million)

Table 43： Global Oligonucleotide Therapeutics Revenue Forecast Analysis by Application (2026-2032) & (US$ Million)

Table 44： Oligonucleotide Therapeutics Typical Customer List

Table 45： Oligonucleotide Therapeutics Distributors List

Figure 1： Oligonucleotide Therapeutics Product Pictures

Figure 2： Antisense Oligonucleotide Picture Scope

Figure 3： Aptamer Picture Scope

Figure 4： Others Picture Scope

Figure 5： Neuromuscular Diseases Picture Scope

Figure 6： ATTR Picture Scope

Figure 7： Hepatic VOD Picture Scope

Figure 8： Others Picture Scope

Figure 9： Global Oligonucleotide Therapeutics Market Size Analysis：2024 VS 2025 VS 2032 (US$ Million)

Figure 10： Global Oligonucleotide Therapeutics Market Revenue and Growth Rate Analysis: (2020-2032) & (US$ Million)

Figure 11： Global Oligonucleotide Therapeutics Revenue Market Share by Country in 2024

Figure 12： United States Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 13： Germany Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 14： Japan Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 15： China Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 16： France Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 17： U.K. Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 18： South Korea Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 19： Canada Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 20： Italy Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 21： Russia Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 22： Mexico Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 23： Brazil Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 24： India Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 25： Vietnam Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 26： Thailand Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 27： South Africa Oligonucleotide Therapeutics Market Revenue and Growth Rate (2020-2032) & (US$ Million)

Figure 28： Global Oligonucleotide Therapeutics Revenue Market Share by Key Manufacturers in 2024

Figure 29： Global Oligonucleotide Therapeutics Industry Competition Landscape

Figure 30： Global Oligonucleotide Therapeutics Market Size by Type 2020-2032 (US$ Million)

Figure 31： Global Oligonucleotide Therapeutics Market Share by Type: 2025 & 2032

Figure 32： Oligonucleotide Therapeutics Industry Chain Analysis

Figure 33： Global Oligonucleotide Therapeutics Revenue Market Share by Application (2020-2032)

Figure 34： Key Interview Objectives

Figure 35： Bottom-Up and Top-Down Research Methods